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1

7. Gene delivery and biodistribution in the brain and spinal cord following intrathecal administration of adeno-associated virus serotype 5 vector

Lalitha Belur, Carolyn Fairbanks, Lucy Vulchanova, Kelly Podetz-Pedersen, Walter Low, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

2

Facilitated transport of uracil and 5-fluorouracil, and permeation of orotic acid into cultured mammalian cells

Robert M. Wohlhueter, R. Scott McIvor, Peter G. W. Plagemann

Journal:

Journal of Cellular Physiology

Year:

1980

Language:

english

File:

PDF, 909 KB

english, 1980

3

ZFN-mediated in vivo genome editing of hepatocytes results in phenotypic correction in murine MPS I and MPS II models

Wechsler, Thomas, DeKelver, Russell, Laoharawee, Kanut, Ou, Li, Tom, Susan, Radecke, Robert, Sproul, Scott, Koniar, Brenda L., Podetz-Perdersen, Kelly, Cooksley, Renee D., Meyer, Kathleen, McIvor, Sco

Journal:

Molecular Genetics and Metabolism

Year:

2018

Language:

english

File:

PDF, 70 KB

english, 2018

4

Modifiable Risk Factors for Vascular Access Site Complications in the IMPACT II Trial of Angioplasty With Versus Without Eptifibatide

Jeffrey S. Mandak, James C. Blankenship, Laura H. Gardner, Scott D. Berkowitz, Frank V. Aguirre, Kristina N. Sigmon, Gerald C. Timmis, Ian C. Gilchrist, Michael McIvor, Jon Resar, Bonnie H. Weiner, Ba

Journal:

Journal of the American College of Cardiology

Year:

1998

Language:

english

File:

PDF, 75 KB

english, 1998

5

107. Syngeneic bone marrow transplantation in a murine model of mucopolysaccharidosis type I

Daniel A. Wolf, Kelly M. Podetz-Pedersen, Jennifer L. Gori, Walter C. Low, Chester B. Whitley, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 44 KB

english, 2008

6

Spatial Navigation and Working Memory Tests Demonstrate Neurological Deficits in a Murine Model of Mucopolysaccharidosis Type II (Hunter Syndrome)

Zhenhong Crusoe Nan, Kelly M. Podetz-Pedersen, Joseph Muenzer, Walter C. Low, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

7

Human Nerve Growth Factor Receptor and Cytosine Deaminase Fusion Genes

Lewis, Victor A., Basso, Lisa, Blake, Noel, Salo, Jill, Lund, Troy C., McIvor, R. Scott, Orchard, Paul J.

Journal:

Human Gene Therapy

Year:

2003

Language:

english

File:

PDF, 317 KB

english, 2003

8

706. Non-Invasive Intranasal Administration of AAV9-Iduronidase Prevents Emergence of Neurologic Disease and Neurocognitive Dysfunction in a Murine Model of Mucopolysaccharidosis Type I

Belur, Lalitha, Buckvold, Megan, Podetz-Pedersen, Kelly, Riedl, Maureen, Vulchanova, Lucy, Hanson, Leah R., Kozarsky, Karen, Frey, William H., Low, Walter C., Fairbanks, Carolyn, Scott McIvor, R.

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 271 KB

english, 2015

9

Sleeping Beauty-mediated correction of Fanconi anemia type C

Kendra A. Hyland, Erik R. Olson, Karl J. Clark, Elena L. Aronovich, Perry B. Hackett, Bruce R. Blazar, Jakub Tolar, R. Scott McIvor

Journal:

The Journal of Gene Medicine

Year:

2011

Language:

english

File:

PDF, 228 KB

english, 2011

10

“Supercharged Cells” for Delivery of Recombinant Human Iduronate-2-Sulfatase

Dao Pan, Jon J. Jonsson, Stephen E. Braun, R.Scott McIvor, Chester B. Whitley

Journal:

Molecular Genetics and Metabolism

Year:

2000

Language:

english

File:

PDF, 166 KB

english, 2000

11

Prolonged High-Level Expression of IDUA from Sleeping Beauty Transposons in Immunocompetent Mice

Elena Aronovich, Jason Bell, Kelly Podetz-Petersen, Brenda Koniar, R. Scott McIvor, Perry Hackett

Journal:

Molecular Genetics and Metabolism

Year:

2012

Language:

english

File:

PDF, 57 KB

english, 2012

12

Gene therapy for chronic myelogenous leukemia

Catherine M. Verfaillie, R.Scott McIvor, Robert C.H. Zhao

Journal:

Molecular Medicine Today

Year:

1999

Language:

english

File:

PDF, 210 KB

english, 1999

13

Gene therapy for neurologic manifestations of mucopolysaccharidoses

Wolf, Daniel A, Banerjee, Sharbani, Hackett, Perry B, Whitley, Chester B, McIvor, R Scott, Low, Walter C

Journal:

Expert Opinion on Drug Delivery

Year:

2015

Language:

english

File:

PDF, 340 KB

english, 2015

14

Therapeutic Delivery of mRNA: The Medium Is the Message

Scott McIvor, R

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 212 KB

english, 2011

15

Metabolic Correction and Cross-Correction of Mucopolysaccharidosis Type II (Hunter Syndrome) by Retroviral-Mediated Gene Transfer and Expression of Human Iduronate-2-Sulfatase

Stephen E. Braun, Elena L. Aronovich, Rose Ann Anderson, Paul L. Crotty, R. Scott McIvor and Chester B. Whitley

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.15 MB

english, 1993

16

Intrathecal and intranasal infusion of adeno-associated virus vector: non-invasive routes of administration achieving corrective levels of iduronidase expression throughout the brain for gene therapy of mucopolysaccharidosis type I

McIvor, R. Scott, Nan, Zhenhong, Podetz-Pedersen, Kelly M., Kitto, Kelley, Hanson, Leah R., Wolf, Daniel A., Kozarsky, Karen, Fairbanks, Carolyn A., Frey, William H., Low, Walter C., Belur, Lalitha R.

Journal:

Molecular Genetics and Metabolism

Year:

2014

Language:

english

File:

PDF, 77 KB

english, 2014

17

Designing Protein Dimerizers: The Importance of Ligand Conformational Equilibria

Carlson, Jonathan C. T., Kanter, Aaron, Thuduppathy, Guruvasuthevan R., Cody, Vivian, Pineda, Pamela E., McIvor, R. Scott, Wagner, Carston R.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 271 KB

english, 2003

18

Gene Expression in Lung and Liver After Intravenous Infusion of Polyethylenimine Complexes of Sleeping Beauty Transposons

Podetz-Pedersen, Kelly M., Bell, Jason B., Steele, Terry W.J., Wilber, Andrew, Shier, W. Thomas, Belur, Lalitha R., McIvor, R. Scott, Hackett, Perry B.

Journal:

Human Gene Therapy

Year:

2010

Language:

english

File:

PDF, 14.05 MB

english, 2010

19

An improved enzymatic radioassay for ribose 1-phosphate

R.Scott McIvor, Robert M. Wohlhueter, Peter G.W. Plagemann

Journal:

Analytical Biochemistry

Year:

1982

Language:

english

File:

PDF, 436 KB

english, 1982

20

A method for lifelong genetic manipulation of regenerating hepatocytes in mouse

Wangensteen, Kirk J, Wilber, Andrew, Keng, Vincent W, Chen, Yixin, Matise, Ilze, Wangensteen, Laura, Steer, Clifford J, McIvor, R Scott, Largaespada, David A, Wang, Xin

Journal:

Year:

2008

Language:

english

File:

PDF, 235 KB

english, 2008

21

Awakening gene therapy with Sleeping Beauty transposons

Jeffrey J Essner, R Scott McIvor, Perry B Hackett

Journal:

Current Opinion in Pharmacology

Year:

2005

Language:

english

File:

PDF, 152 KB

english, 2005

22

86. Ex vivo lentiviral gene transfer targeting hematopoietic stem cells for therapy of mucopolysaccharidosis type II, Hunter syndrome

R. Scott McIvor, Daniel A. Wolf, Kelly Podetz-Petersen, Zhenhong Nan, Chester B. Whitley, Joseph Muenzer, Paul J. Orchard, Walter C. Low

Journal:

Molecular Genetics and Metabolism

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

23

Sleeping Beauty Transposon‐mediated Engineering of Human Primary T Cells for Therapy of CD19+ Lymphoid Malignancies

Huang, Xin, Guo, Hongfeng, Kang, Johnthomas, Choi, Suet, Zhou, Tom C, Tammana, Syam, Lees, Christopher J, Li, Zhong‐Ze, Milone, Michael, Levine, Bruce L, Tolar, Jakub, June, Carl H, Scott McIvor, R, W

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 697 KB

english, 2008

24

997. Immune-Mediated Loss of Transgene Expression in Mouse Liver Following Transposon Delivery

Aronnovich, Elena L., Bell, Jason B., Gunther, Roland, Koniar, Brenda, Frantz, Aric, Matise, Ilze, McIvor, R. Scott, Whitley, Chester B., Hackett, Perry B.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 89 KB

english, 2006

25

Atovaquone Suspension Compared with Aerosolized Pentamidine for Prevention of Pneumocystis carinii Pneumonia in Human Immunodeficiency Virus–Infected Subjects Intolerant of Trimethoprim or Sulfonamides

Chan, Charles, Montaner, Julio, Lefebvre, Eric‐Albert, Morey, Gary, Dohn, Michael, McIvor, R. Andrew, Scott, Janna, Marina, Raymond, Caldwell, Paul

Journal:

The Journal of Infectious Diseases

Year:

1999

Language:

english

File:

PDF, 89 KB

english, 1999

26

Clinical-Scale Selection of Anti-CD3/CD28–Activated T Cells After Transduction with a Retroviral Vector Expressing Herpes Simplex Virus Thymidine Kinase and Truncated Nerve Growth Factor Receptor

Orchard, Paul J., Blazar, Bruce R., Burger, Scott, Levine, Bruce, Basso, Lisa, Nelson, David M.K., Gordon, Keith, McIvor, R. Scott, Wagner, John E., Miller, Jeffrey S.

Journal:

Human Gene Therapy

Year:

2002

Language:

english

File:

PDF, 209 KB

english, 2002

27

Harnessing a High Cargo-Capacity Transposon for Genetic Applications in Vertebrates

Balciunas, Darius, Wangensteen, Kirk J., Wilber, Andrew, Bell, Jason, Geurts, Aron, Sivasubbu, Sridhar, Wang, Xin, Hackett, Perry B., Largaespada, David A., McIvor, R. Scott, Ekker, Stephen C.

Journal:

Year:

2006

Language:

english

File:

PDF, 348 KB

english, 2006

28

Retroviral-Mediated Transfer of the Iduronate-2-Sulfatase Gene into Lymphocytes for Treatment of Mild Hunter Syndrome (Mucopolysaccharidosis Type II). University of Minnesota Medical School, Minneapolis, Minnesota

Whitley, Chester B., McIvor, R. Scott, Aronovich, Elena L., Berry, Susan A., Blazar, Bruce R., Burger, Scott R., Kersey, John H., King, Richard A., Faras, Anthony J., Latchaw, Richard E., McCullough,

Journal:

Human Gene Therapy

Year:

1996

Language:

english

File:

PDF, 1.24 MB

english, 1996

29

AAV9 mediated correction of iduronate-2-sulfatase deficiency in the central nervous system of mucopolysaccharidosis type II mice

Laoharawee, Kanut, Podetz-Petersen, Kelly M., Kitto, Kelley F., Vulchanova, Lucy, Fairbanks, Carolyn A., Kozarsky, Karen, Low, Walter C., Scott McIvor, R.

Journal:

Molecular Genetics and Metabolism

Year:

2016

Language:

english

File:

PDF, 47 KB

english, 2016

30

369. AAV9 Mediated Correction of Iduronate-2-Sulfatase Deficiency in the Central Nervous System of Mucopolysaccharidosis Type II Mice

Laoharawee, Kanut, Podetz-Pedersen, Kelly M., Kitto, Kelley, Vulchanova, Lucy, Fairbanks, Carolyn, Kozarsky, Karen, Low, Walter C., Scott McIvor, R.

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 276 KB

english, 2015

31

37. Comparison of gene expression in vivo from Sleeping Beauty transposons after hydrodynamic delivery or condensation by polyethylenimine and cationic lipids

Perry Hackett, Kelly Podetz-Pedersen, Jason Bell, Elena Aronovich, Betsy Kren, Chester Whitley, Wouter Driessen, Sean Sullivan, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 45 KB

english, 2008

32

Comparison of intraventricular vs. endovascular AAV5 mediated IDUA gene delivery to the brain in the MPS-I mouse model

Christopher Janson, Crusoe Nan, Lalitha Belur, Scott McIvor, Walter Low

Journal:

Molecular Genetics and Metabolism

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

33

Pax3-induced expansion enables the genetic correction of dystrophic satellite cells

Filareto, Antonio, Rinaldi, Fabrizio, Arpke, Robert W., Darabi, Radbod, Belanto, Joseph J., Toso, Erik A., Miller, Auston Z., Ervasti, James M., McIvor, R. Scott, Kyba, Michael, Perlingeiro, Rita CR

Journal:

Skeletal Muscle

Year:

2015

Language:

english

File:

PDF, 1.95 MB

english, 2015

34

Antisense RNA Sequences Modulating the Ataxin-1 Message: Molecular Model of Gene Therapy for Spinocerebellar Ataxia Type 1, a Dominant-Acting Unstable Trinucleotide Repeat Disease

Gao, Youxin, Zu, Tao, Low, Walter C., Orr, Harry T., McIvor, R. Scott

Journal:

Cell Transplantation

Year:

2008

Language:

english

File:

PDF, 249 KB

english, 2008

35

A Broad Range of Dose Optima Achieve High-level, Long-term Gene Expression After Hydrodynamic Delivery of Sleeping Beauty Transposons Using Hyperactive SB100x Transposase

Podetz-Pedersen, Kelly M, Olson, Erik R, Somia, Nikunj V, Russell, Stephen J, McIvor, R Scott

Journal:

Molecular Therapy — Nucleic Acids

Year:

2016

Language:

english

File:

PDF, 335 KB

english, 2016

36

Conditional gene expression in the mouse using aSleeping Beautygene-trap transposon

Aron M Geurts, Andrew Wilber, Corey M Carlson, Paul D Lobitz, Karl J Clark, Perry B Hackett, R Scott McIvor, David A Largaespada

Journal:

BMC Biotechnology

Year:

2006

Language:

english

File:

PDF, 1.30 MB

english, 2006

37

Simple and Efficient Methods for Enrichment and Isolation of Endonuclease Modified Cells

Moriarity, Branden S., Rahrmann, Eric P., Beckmann, Dominic A., Conboy, Caitlin B., Watson, Adrienne L., Carlson, Daniel F., Olson, Erik R., Hyland, Kendra A., Fahrenkrug, Scott C., McIvor, R. Scott,

Journal:

Year:

2014

Language:

english

File:

PDF, 2.00 MB

english, 2014

38

Mild preconditioning and low-level engraftment confer methotrexate resistance in mice transplanted with marrow expressing drug-resistant dihydrofolate reductase activity

James, Rohaizah I., Warlick, Christopher A., Diers, Miechaleen D., Gunther, Roland, McIvor, R. Scott

Journal:

Year:

2000

File:

PDF, 223 KB

2000

39

Adeno-associated virus type 2 vectors: transduction and long-term expression in cerebellar Purkinje cells in vivo is mediated by the fibroblast growth factor receptor 1

Lalitha R. Belur, William F. Kaemmerer, R. Scott McIvor, Walter C. Low

Journal:

Archives of Virology

Year:

2008

Language:

english

File:

PDF, 239 KB

english, 2008

40

64. Targeting neural stem cells in the mammalian brain with intraventricular injections of lenti, AAV5, or Sleeping Beauty vectors

Walter Low, Terry Burns, Catherine Verfaillie, Perry Hackett, Chet Whitley, Zhenghong Nan, Feng Xiao, Lalitha Belur, Zach Demorest, Dan Wolf, John Ohlfest, Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 43 KB

english, 2008

41

Lysosomal enzyme can bypass the blood–brain barrier and reach the CNS following intranasal administration

Daniel A. Wolf, Leah R. Hanson, Elena L. Aronovich, Zhenhong Nan, Walter C. Low, William H. Frey II, R. Scott McIvor

Journal:

Molecular Genetics and Metabolism

Year:

2012

Language:

english

File:

PDF, 424 KB

english, 2012

42

In vivo protection of activated Tyr22-dihydrofolate reductase gene-modified canine T lymphocytes from methotrexate

Gori, Jennifer L., Beard, Brian C., Williams, Nathaniel P., Ironside, Christina, Swanson, Debra, Scott McIvor, R., Kiem, Hans-Peter

Journal:

The Journal of Gene Medicine

Year:

2013

Language:

english

File:

PDF, 629 KB

english, 2013

43

Dihydrofolate Reductase Mutant with Exceptional Resistance to Methotrexate but Not to Trimetrexate

Pineda, Pamela, Kanter, Aaron, McIvor, R. Scott, Benkovic, Stephen J., Rosowsky, Andre, Wagner, Carston R.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 54 KB

english, 2003

44

Characterization of the Human Artemis Promoter by Heterologous Gene Expression In Vitro and In Vivo

Multhaup, Megan M., Gurram, Sweta, Podetz-Pedersen, Kelly M., Karlen, Andrea D., Swanson, Debra L., Somia, Nikunj V., Hackett, Perry B., Cowan, Morton J., McIvor, R. Scott

Journal:

DNA and Cell Biology

Year:

2011

Language:

english

File:

PDF, 680 KB

english, 2011

45

Efficient Non-Viral Integration and Stable Gene Expression in Multipotent Adult Progenitor Cells

Wilber, Andrew, Ulloa Montoya, Fernando, Hammer, Luke, Moriarity, Branden S., Geurts, Aron M., Largaespada, David A., Verfaillie, Catherine M., McIvor, R. Scott, Lakshmipathy, Uma

Journal:

Stem Cells International

Year:

2011

Language:

english

File:

PDF, 3.68 MB

english, 2011

46

Mucopolysaccharidosis Type I: A Review of the Natural History and Molecular Pathology

Hampe, Christiane S., Eisengart, Julie B., Lund, Troy C., Orchard, Paul J., Swietlicka, Monika, Wesley, Jacob, McIvor, R. Scott

Journal:

Year:

2020

File:

PDF, 1.54 MB

2020

47

Efficient and Stable Transgene Expression in Human Embryonic Stem Cells Using Transposon-Mediated Gene Transfer

Andrew Wilber, Jonathan L. Linehan, Xinghui Tian, Petter S. Woll, Julie K. Morris, Lalitha R. Belur, R. Scott McIvor, Dan S. Kaufman

Journal:

Year:

2007

Language:

english

File:

PDF, 2.02 MB

english, 2007

48

Assay for expression of methotrexate-resistant dihydrofolate reductase activity in the presence of drug-sensitive enzyme

Kirstin Thompson, Dani Bich-Nga Vinh, R. Scott McIvor

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

1992

Language:

english

File:

PDF, 734 KB

english, 1992

49

65. Gene therapy of MPS I mice using the Sleeping Beauty Transposon system

Perry Hackett, Elena Aronovich, Jason Bell, Shaukat Khan, Roland Gunther, Josh Parker, Cathy Carlson, Chester Whitley, R. Scott McIvor, Pankaj Gupta

Journal:

Molecular Genetics and Metabolism

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

50

Long-Term Transgene Expression and Survival of Transgene-Expressing Grafts Following Lentivirus Transduction of Bone Marrow Side Population Cells

Zhang, Jai-lin, Cai, Jin, Jackson, John D., Kuszynski, Charles A., Walls, Shannon, McIvor, R Scott, Fox, Ira J.

Journal:

Transplantation Journal

Year:

2005

Language:

english

File:

PDF, 652 KB

english, 2005

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